Fabrication and characterization of two types of bone composites made of chitosan-genipin hydrogel and Bioglass 45S5

Synthetic inorganic-organic composites are of interest for bone tissue engineering as an alternative to natural grafts, since they resemble the structure and degrade over time, enabling new grow. In this study, properties two types composite materials: Type 1) genipin cross-linked chitosan hydrogels with addition Bioglass 45S5 (BG) powder 2) BG scaffolds coated hydrogel, have been investigated using scanning electron microscopy (SEM), FTIR spectroscopy, fluorescence intensity (FI) measurement compression tests. The were immersed in simulated body fluid (SBF) up 2 weeks their mechanical examined. Results showed that improved compressive stress both before after immersion SBF. However, low values do not make them suitable applications. case chitosan-genipin coating Hydrogel potential load-bearing applications, commonly used collagen hydroxyapatite.